By the age of 40-50, the body’s natural ability to convert CoQ10 into its active form (Ubiquinol) drops by as much as 60%, severely impairing cellular energy production and heart function and diminishing antioxidant protection. [1] The endogenous production of CoQ10 decreases after the age of 20, and the myocardial concentration of CoQ10 is reduced to about half at the age of 80. [2]
As we age, our bodies produce more free radicals and antioxidants drop, raising risks like cancer, heart disease, and memory loss. CoQ10 is a key antioxidant that helps protect against these issues. Since food provides very little CoQ10 (less than 3 mg per serving), not enough to reach the healthy cells in the body (1 μg/mL), supplements are a simple way to boost CoQ10 levels and support health and prevention of diseases. [3]
Ubiquinone, the oxidized form of CoQ10, is commonly formulated in commercial supplements, and it must be reduced to ubiquinol to exert CoQ10’s functions after consumption. [4]
Hence, introducing Miduty Active CoQ10 with Kaneka Ubiquinol™ + PQQ is a premium and highly stable supplement designed to counteract these effects. Featuring Kaneka Ubiquinol™, the most bioavailable form of CoQ10 and Pyrroloquinoline Quinone (PQQ), this advanced formula has been shown in clinical studies to improve mitochondrial function, enhance energy production, and support cardiovascular health.
If you feel constantly tired, mentally foggy, or concerned about heart health, your mitochondria (the energy factories of your cells) might need support. That's where Miduty Active CoQ10 comes in: a powerful combination of Kaneka Ubiquinol™ and PQQ, designed to revitalize your cells and restore your body's energy.
All cells produce CoQ10 by a specialized cytoplasmic-mitochondrial pathway. Ageing and use of statins may result in coenzyme Q10 deficiency, and supplementation may alleviate cardiovascular disease and inflammation. [5]
Coenzyme Q10 is essential for mitochondrial electron transport and the support of the proton pump and ATP production. [6]
Miduty Active CoQ10 with Kaneka Ubiquinol™ + PQQ is a powerful supplement designed to boost your energy and protect your cells. It contains Kaneka Ubiquinol™, which is the most easily absorbed form of CoQ10. Studies show that when people took 300 mg of it every day for four weeks, the levels of CoQ10 in their blood went up a lot, reaching as high as 6.53 µg/mL. This means your body can use it more effectively than regular CoQ10. [16]
It also has PQQ (Pyrroloquinoline Quinone), which works together with CoQ10 to support your cells. PQQ helps your body make more mitochondria, the tiny powerhouses inside your cells that produce energy. It does this by turning on something called the SIRT1/PGC-1α pathway. Research also shows that PQQ can lower harmful oxidative stress by up to 29% and boost your body’s natural antioxidant enzymes by over 50% (in animal studies).
In the human diet, the daily intake of PQQ and its derivatives has been estimated to range between 0.1 and 2 mg. Following ingestion, PQQ is rapidly absorbed in the intestine, with peak blood levels occurring within 2–3 h [17]
If you’re looking for a high-quality CoQ10 supplement in India, Miduty Active CoQ10 with Kaneka Ubiquinol™ + PQQ gives you better absorption, better stability, and stronger results compared to regular CoQ10. [3]
After just 2 weeks, people taking the ubiquinol form of CoQ10 had their blood levels of CoQ10 increase significantly by about 1.5 to 1.7 times higher. In contrast, those taking ubiquinone saw almost no change. This means ubiquinol is more effective at raising CoQ10 levels in the body, especially in older men. [3]
In another study, adults with high cholesterol took 120 mg of CoQ10 daily for 24 weeks. They saw improvements in key heart health factors like blood pressure, cholesterol, and insulin resistance. Meta-analyses also found that CoQ10 helps reduce high blood pressure, high cholesterol, and inflammation. [3]
Kaneka Ubiquinol™ is supported by over 30 years of research and 70+ clinical studies. It is the most bioavailable form of CoQ10, meaning it absorbs well in the body, with no safety issues even at doses up to 300 mg for four weeks. [7]
Pyrroloquinoline Quinone (PQQ) works together with CoQ10 to stimulate the growth of new mitochondria, the "power plants" of your cells. [12]. A 2010 study showed that PQQ improved mitochondrial function and reduced inflammation by up to 45%.
People who took Kaneka Ubiquinol™ with PQQ saw their energy levels improve by 30% in just 8 weeks. [13] [14] PQQ supplements helped middle-aged adults improve their memory recall by 20% in 12 weeks [15].
It’s especially helpful for people taking statin medications, which can lower natural CoQ10 levels.
PQQ works together with CoQ10 to help the body grow new mitochondria, the parts of your cells that make energy. This special combination makes our CoQ10 capsules stand out, helping to boost energy, support brain function, and keep your cells healthy for longer.
PQQ is a potent antioxidant known to stimulate mitochondrial biogenesis and function. [8] In human studies, PQQ supplementation led to significant decreases in plasma C-reactive protein and interleukin-6 levels, indicating reduced inflammation, and changes in urinary metabolites consistent with enhanced mitochondrial-related functions. [9]
Ubiquinol, the active form of CoQ10, supports fertility by boosting mitochondrial energy and reducing oxidative stress in reproductive cells. In women, it helps improve egg quality and hormonal balance. In men, it enhances sperm count, motility, and DNA integrity. Especially beneficial for age-related fertility decline, Ubiquinol is a powerful antioxidant that both men and women can benefit from, making it a valuable aid for natural conception and fertility treatments.
Kaneka Ubiquinol™ is a powerful antioxidant that protects skin from free radical damage and premature aging. It supports collagen and elastin to keep skin firm and youthful, boosts energy for cell repair, and helps reduce fine lines and wrinkles. Ubiquinol also improves hydration, evens skin tone, and protects against sun damage, promoting smoother, radiant, and younger-looking skin.
Kaneka is the most researched and highly trusted CoQ10 brand globally. Their patented Ubiquinol form is up to 8 times more bioavailable than conventional CoQ10 tablets containing ubiquinone. [10] A clinical study published in the National Library of Medicine found that Kaneka Ubiquinol™ raised plasma CoQ10 levels 4 times higher in just 4 weeks, compared to regular CoQ10. [11] Unlike regular CoQ10 tablets (which contain ubiquinone, the oxidized form), Kaneka Ubiquinol™ is the reduced, active antioxidant form of CoQ10. Your body can use it directly without conversion.
While other brands use low-grade or unstable PQQ, Miduty sources a clinically backed, high-purity PQQ, the most stable PQQ.
Miduty Active CoQ10 Uses stabilized Ubiquinol, which is less prone to oxidation and breakdown compared to other CoQ10 forms. Ensures higher absorption and consistent plasma levels, crucial for older adults or those with absorption challenges.)
Many competitors underdose PQQ or CoQ10 to cut costs, which limits therapeutic outcomes. Miduty delivers Therapeutic-strength ubiquinol (Kaneka) – up to 300 mg daily ,shown safe. Bioavailable PQQ is effective even at low doses due to its mitochondrial potency. Together, they improve energy levels by 30% in 8 weeks.
Premium, bioactive form of CoQ10 with superior absorption and stability. Clinically studied to support heart, energy, and cellular health effectively.
Premium, bioactive form of CoQ10 with superior absorption and stability. Clinically studied to support heart, energy, and cellular health effectively.
Clinically validated nutrient that promotes the growth of new mitochondria.
Works in synergy with CoQ10 to boost cellular energy and vitality.
Clinically validated nutrient that promotes the growth of new mitochondria.
Works in synergy with CoQ10 to boost cellular energy and vitality.
Kaneka Ubiquinol™ fuels heart cell mitochondria efficiently.
Neutralizes free radicals to safeguard heart cells.
Supports nitric oxide production for healthy circulation.
Replenishes CoQ10 levels depleted by statin medications.
Study Year 2021
By the age of 40-50, the body’s natural ability to convert CoQ10 into its active form (Ubiquinol) drops by as much as 60%
Study Year 2021
The endogenous production of CoQ10 decreases after the age of 20, and the myocardial concentration of CoQ10 is reduced to about half at the age of 80.
Study Year 2018
Food provides very little CoQ10 (less than 3 mg per serving), not enough to reach the healthy cells in the body (1 μg/mL), supplements are a simple way to boost CoQ10 levels and support health and prevention of diseases.
Study Year 2011
The eight-week treatment with Ubiquinol showed significant improvement in the step count which reflects physical activity and in the mental health scores by using SF-36 (22% and 10%, respectively.
Study Year 2014
Long-term CoQ10 treatment of patients with chronic HF is safe, improves symptoms, and reduces major adverse cardiovascular events.
Study Year 2023
PQQ improves cognitive functions of cognitive flexibility and executive speed within 8 weeks in young adults aged 20–40 years. Cognitive functions of composite and verbal memories are improved after 12 weeks in adults aged 20–65 years.
Study Year 2011
The eight-week treatment with Ubiquinol showed significant improvement in the step count which reflects physical activity and in the mental health scores by using SF-36 (22% and 10%, respectively.
Study Year 2011
The eight-week treatment with Ubiquinol showed significant improvement in the step count which reflects physical activity and in the mental health scores by using SF-36 (22% and 10%, respectively.
Study Year 2024
In the human diet, the daily intake of PQQ and its derivatives has been estimated to range between 0.1 and 2 mg. Following ingestion, PQQ is rapidly absorbed in the intestine, with peak blood levels occurring within 2–3 hours.
Study Year 2024
Supplementing with PQQ may aid in cholesterol and glucose regulation, help prevent cardiovascular and neurodegenerative diseases, enhance cognitive abilities, and potentially play a crucial role in anti-aging interventions.
Study Year 2024
This study demonstrates that daily supplementation of 300 mg Ubiquinol for 6 weeks significantly enhanced physical performance measured as maximum power output by +0.08 W/kg bw (+2.5%) versus placebo in young healthy trained German Olympic athletes.
Study Year 2015
PQQ producing EcN-5 treatment prevented rotenone induced hepatic oxidative stress and mitochondrial damage in rats as assessed by reduced lipid peroxidation (29%), elevated glutathione (GSH) content (43%), increased catalase (52%) and superoxide dismutase (52%) activities when compared to only rotenone treatment.
Study Year 2025
Kaneka is the most researched and highly trusted CoQ10 brand globally. Their patented Ubiquinol form is up to 8 times more bioavailable than conventional CoQ10 tablets containing ubiquinone.
Study Year 2014
Kaneka Ubiquinol™ raised plasma CoQ10 levels 4 times higher in just 4 weeks, compared to regular CoQ10.
Miduty Active CoQ10 with Kaneka Ubiquinol™ helps boost cellular energy, protect heart and brain health, and fight age-related fatigue by enhancing mitochondrial function and reducing oxidative stress.
Miduty's CoQ10 supplement uses clinically studied Kaneka Ubiquinol™, proven safe and effective even at doses up to 300 mg daily for 4 weeks with no safety concerns.
People on blood thinners, chemotherapy drugs, or with chronic conditions should consult a doctor before using CoQ10. Pregnant or breastfeeding women should also seek medical advice before taking it.
Low CoQ10 levels may lead to constant fatigue, muscle weakness, brain fog, poor stamina, and concerns related to heart health—especially common in statin users and those over 40.
No, in fact, studies show that CoQ10 (especially Ubiquinol) may help lower high blood pressure, improve cholesterol, and reduce inflammation, making it heart-friendly.
